Patientenkolloquium 2019
Das Universitätsklinikum Bonn möchte Sie auch 2019 wieder für das Patientenkolloquium "Uni-Medizin für Sie: Mitten im Leben" herzlich einladen ... weiterlesen


Stand 14.04.2015

Veröffentlichungen 2014
Nieratschker V, Grosshans M, Frank J, Strohmaier J, von der Goltz C, El-Maarri O, Witt SH, Cichon S, Nöthen MM, Kiefer F, Rietschel M
Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age.
Addict Biol. 2014;19(2): 305-11

Biswas A, Ivaskevicius V, Thomas A, Varvenne M, Brand B, Rott H, Haussels I, Ruehl H, Scholz U, Klamroth R, Oldenburg J
Eight novel F13A1 gene missense mutations in patients with mild FXIII deficiency: in silico analysis suggests changes in FXIII-A subunit structure/function.
Ann Hematol. 2014;93(10): 1665-76

Penner AH, Berens C, Wolf D, Mayer K
Paraneoplastic disseminated intravascular coagulation caused by splenic littoral cell angioma.
Ann Hematol. 2014;93(10): 1795-6

Dauksa A, Gulbinas A, Endzinas Z, Oldenburg J, El-Maarri O
DNA methylation at selected CpG sites in peripheral blood leukocytes is predictive of gastric cancer.
Anticancer Res. 2014;34(10): 5381-8

Schreiner C, Suter S, Watzka M, Hertfelder HJ, Schreiner F, Oldenburg J, Bartmann P, Heep A
Genetic variants of the vitamin K dependent coagulation system and intraventricular hemorrhage in preterm infants.
BMC Pediatr. 2014;14: 219

Al Chawa T, Ludwig KU, Fier H, Pötzsch B, Reich RH, Schmidt G, Braumann B, Daratsianos N, Böhmer AC, Schuencke H, Alblas M, Fricker N, Hoffmann P, Knapp M, Lange C, Nöthen MM, Mangold E
Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.
Birth Defects Res A Clin Mol Teratol. 2014;100(6): 493-8

Collins PW, Young G, Knobe K, Karim FA, Angchaisuksiri P, Banner C, Gürsel T, Mahlangu J, Matsushita T, Mauser-Bunschoten EP, Oldenburg J, Walsh CE, Negrier C, paradigm 2 Investigators
Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial.
Blood. 2014;124(26): 3880-6

    Czogalla KJ, Biswas A, Rost S, Watzka M, Oldenburg J
    The Arg98Trp mutation in human VKORC1 causing VKCFD2 disrupts a di-arginine-based ER retention motif.
    Blood. 2014;124(8): 1354-62

    Minford A, Behnisch W, Brons P, David M, Gomez Gomez N, Hertfelder HJ, Kruempel A, Kurnik K, Mathias M, Molines Honrubia A, Monagle P, Morgan M, Nowak-Göttl U, Olivieri M
    Subcutaneous protein C concentrate in the management of severe protein C deficiency--experience from 12 centres.
    Br J Haematol. 2014;164(3): 414-21

    Yassin AA, Elwaseef AM, Elnashar MM, Oldenburg J, Mayer G, Pötzsch B, Müller J
    Protamine-adsorbed magnetic nanoparticles for efficient isolation and concentration of hepatitis-C virus from human plasma samples.
    Chem Commun (Camb). 2014;50(5): 590-2

    Sido B, Dumoulin FL, Homann J, Hertfelder HJ, Bollmann M, Molderings GJ
    [Surgical interventions in patients with mast cell activation disease. Aspects relevant for surgery using the example of a cholecystectomy].
    Chirurg. 2014;85(4): 327-33

    Schreiner F, Gohlke B, Stutte S, Bartmann P, Hecher K, Oldenburg J, El-Maarri O, Woelfle J
    11p15 DNA-methylation analysis in monozygotic twins with discordant intrauterine development due to severe twin-to-twin transfusion syndrome.
    Clin Epigenetics. 2014;6(1): 6
      Goodeve AC, Pavlova A, Oldenburg J
      Genomics of bleeding disorders.
      Haemophilia. 2014;20 Suppl 4: 50-3

      Kriegsmann M, Casadonte R, Randau T, Gravius S, Pennekamp P, Strauss A, Oldenburg J, Wieczorek K, Deininger SO, Otto M, Kriegsmann J
      MALDI imaging of predictive ferritin, fibrinogen and proteases in haemophilic arthropathy.
      Haemophilia. 2014;20(3): 446-53

      Oldenburg J, Austin SK, Kessler CM
      ITI choice for the optimal management of inhibitor patients - from a clinical and pharmacoeconomic perspective.
      Haemophilia. 2014;20 Suppl 6: 17-26

      Oldenburg J, Albert T
      Novel products for haemostasis - current status.
      Haemophilia. 2014;20 Suppl 4: 23-8

      Oldenburg J, Jiménez-Yuste V, Peiró-Jordán R, Aledort LM, Santagostino E
      Primary and rescue immune tolerance induction in children and adults: a multicentre international study with a VWF-containing plasma-derived FVIII concentrate.
      Haemophilia. 2014;20(1): 83-91

      Pashov AD, Calvez T, Gilardin L, Maillère B, Repessé Y, Oldenburg J, Pavlova A, Kaveri SV, Lacroix- Desmazes S
      In silico calculated affinity of FVIII-derived peptides for HLA class II alleles predicts inhibitor development in haemophilia A patients with missense mutations in the F8 gene.
      Haemophilia. 2014;20(2): 176-84

      Souri M, Biswas A, Misawa M, Omura H, Ichinose A
      Severe congenital factor XIII deficiency caused by novel W187X and G273V mutations in the F13A gene; diagnosis and classification according to the ISTH/SSC guidelines.
      Haemophilia. 2014;20(2): 255-62
        Strauss AC, Goldmann G, Wessling M, Gravius S, Müller MC, Wimmer MD, Wirtz DC, Oldenburg J, Pennekamp PH
        Total ankle replacement in patients with haemophilia and virus infections--a safe alternative to ankle arthrodesis?
        Haemophilia. 2014;20(5): 702-8

        Zimmermann MA, Oldenburg J, Müller CR, Rost S
        Expression studies of mutant factor VIII alleles with premature termination codons with regard to inhibitor formation.
        Haemophilia. 2014;20(3): e215-21

        de Brasi C, El-Maarri O, Perry DJ, Oldenburg J, Pezeshkpoor B, Goodeve A
        Genetic testing in bleeding disorders.
        Haemophilia. 2014;20 Suppl 4: 54-8

        Berger K, Schopohl D, Eheberg D, Oldenburg J, Tiede A, Schramm W
        [Prophylactic factor substitution in severe haemophilia A. Economic assessment in adult patients].
        Hamostaseologie. 2014;34(4): 291-300

        Biswas A, Ivaskevicius V, Thomas A, Oldenburg J
        Coagulation factor XIII deficiency. Diagnosis, prevalence and management of inherited and acquired forms.
        Hamostaseologie. 2014;34(2): 160-6

        Hecking C, Hendelmeier M, von Bardeleben R, Gröschel K, Schinzel H
        Recurrent cerebral ischaemia in a pregnant woman with patent foramen ovale II° and thrombophilia.
        Hamostaseologie. 2014;34(3): 239-43

        Ivaskevicius V, Goldmann G, Horneff S, Marquardt N, Klein C, Albert T, Zeitler H, Oldenburg J
        Inhibitor development and management in three non-severe haemophilia A patients with T295A variant.
        Hamostaseologie. 2014;34 Suppl 1: S9-12

        Oldenburg J, Kurnik K
        Hamburger Hemophilia-Symposium 2013
        Hamostaseologie. 2014;34 1(4A): S3-S3

        Oldenburg J, Müller CR, Rost S, Watzka M, Bevans CG
        Comparative genetics of warfarin resistance.
        Hamostaseologie. 2014;34(2): 143-59

        Oldenburg J
        Genetics in thrombosis and haemostasis.
        Hamostaseologie. 2014;34(2): 111-111

        Pezeshkpoor B, Pavlova A, Oldenburg J, El-Maarri O
        F8 genetic analysis strategies when standard approaches fail.
        Hamostaseologie. 2014;34(2): 167-73

        Strauss AC, Goldmann G, Ezziddin S, Placzek R, Müller MC, Pflugmacher R, Oldenburg J, Pennekamp PH
        Treatment options for haemophilic arthropathy of the elbow after failed conservative therapy. A single centre experience.
        Hamostaseologie. 2014;34 Suppl 1: S17-22

        Wallny TA, Strauss AC, Goldmann G, Oldenburg J, Wirtz DC, Pennekamp PH
        Elective total knee arthroplasty in haemophilic patients. Proposal for a clinical pathway.
        Hamostaseologie. 2014;34 Suppl 1: S23-9

        Morin G, Bruechle NO, Singh AR, Knopp C, Jedraszak G, Elbracht M, Brémond-Gignac D, Hartmann K, Sevestre H, Deutz P, Hérent D, Nürnberg P, Roméo B, Konrad K, Mathieu-Dramard M, Oldenburg J, Bourges-Petit E, Shen Y, Zerres K, Ouadid-Ahidouch H, Rochette J
        Gain-of-Function Mutation in STIM1 (P.R304W) Is Associated with Stormorken Syndrome.
        Hum Mutat. 2014;35(10): 1221-32

        Adjobimey T, Satoguina J, Oldenburg J, Hoerauf A, Layland LE
        Co-activation through TLR4 and TLR9 but not TLR2 skews Treg-mediated modulation of Igs and induces IL-17 secretion in Treg: B cell co-cultures.
        Innate Immun. 2014;20(1): 12-23
          Rühl H, Müller J, Wäschenbach J, Oldenburg J, Dewald O, Pötzsch B
          Short-term venous stasis induces fibrinolytic activation but not thrombin formation.
          J Atheroscler Thromb. 2014;21(12): 1260-70

          Gao C, Liu Y, Zhang H, Zhang Y, Fukuda MN, Palma AS, Kozak RP, Childs RA, Nonaka M, Li Z, Siegel DL, Hanfland P, Peehl DM, Chai W, Greene MI, Feizi T
          Carbohydrate sequence of the prostate cancer-associated antigen F77 assigned by a mucin O-glycome designer array.
          J Biol Chem. 2014;289(23): 16462-77

          Ludwig KU, Böhmer AC, Rubini M, Mossey PA, Herms S, Nowak S, Reutter H, Reutter H, Alblas MA, Lippke B, Barth S, Paredes-Zenteno M, Muñoz-Jimenez SG, Ortiz-Lopez R, Kreusch T, Hemprich A, Martini M, Braumann B, Jäger A, Pötzsch B, Molloy A, Peterlin B, Hoffmann P, Nöthen MM, Rojas- Martinez A, Knapp M, Steegers-Theunissen RP, Mangold E
          Strong association of variants around FOXE1 and orofacial clefting.
          J Dent Res. 2014;93(4): 376-81

          Böhm M, Bäuml CA, Hardes K, Steinmetzer T, Roeser D, Schaub Y, Than ME, Biswas A, Imhof D
          Novel insights into structure and function of factor XIIIa-inhibitor tridegin.
          J Med Chem. 2014;57(24): 10355-65

          Akhter MS, Biswas A, Rashid H, Devi L, Behari M, Saxena R
          Screening of the NOS3 gene identifies the variants 894G/T, 1998C/G and 2479G/A to be associated with acute onset ischemic stroke in young Asian Indians.
          J Neurol Sci. 2014;344(1-2): 69-75

          Akhter MS, Biswas A, Rashid H, Devi L, Behari M, Saxena R
          Screening of the GPX3 gene identifies the "T" allele of the SNP -861A/T as a risk for ischemic stroke in young Asian Indians.
          J Stroke Cerebrovasc Dis. 2014;23(8): 2060-8

          Lingohr P, Bensoukehal S, Matthaei H, Dohmen J, Nadal J, Vilz TO, Koscielny A, Oldenburg J, Kalff JC, Goldmann G
          Value and risk of laparoscopic surgery in hemophiliacs-experiences from a tertiary referral center for hemorrhagic diatheses.
          Langenbecks Arch Surg. 2014;399(5): 609-18

          Singer H, Biswas A, Zimmer N, Messaed C, Oldenburg J, Slim R, El-Maarri O
          NLRP7 inter-domain interactions: the NACHT-associated domain is the physical mediator for oligomeric assembly.
          Mol Hum Reprod. 2014;20(10): 990-1001

          Goltz D, Hittetiya K, Yadegari H, Driesen J, Kirfel J, Neuhaus T, Steiner S, Esch C, Bedorf J, Hertfelder HJ, Fischer HP
          ATZ11 recognizes not only Z-?1-antitrypsin-polymers and complexed forms of non-Z-?1-antitrypsin but also the von Willebrand factor.
          PLoS ONE. 2014;9(3): e91538

          Rühl H, Schröder L, Müller J, Sukhitashvili S, Welz J, Kuhn WC, Oldenburg J, Rudlowski C, Pötzsch B
          Impact of hormone-associated resistance to activated protein C on the thrombotic potential of oral contraceptives: a prospective observational study.
          PLoS ONE. 2014;9(8): e105007

          Oldenburg J, Pezeshkpoor B, Pavlova A
          Historical review on genetic analysis in hemophilia A.
          Semin Thromb Hemost. 2014;40(8): 895-902

          Zeitler H, Ulrich-Merzenich G, Marquardt N, Oldenburg J, Goldmann G
          Immunoadsorption for pregnancy-associated severe acquired hemophilia.
          Ther Apher Dial. 2014;18(1): 103-10

          Luxembourg B, Pavlova A, Geisen C, Spannagl M, Bergmann F, Krause M, Alesci S, Seifried E, Lindhoff- Last E
          Impact of the type of SERPINC1 mutation and subtype of antithrombin deficiency on the thrombotic phenotype in hereditary antithrombin deficiency.
          Thromb Haemost. 2014;111(2): 249-57
            Pahl S, Pavlova A, Driesen J, Oldenburg J
            Effect of F8 B domain gene variants on synthesis, secretion, activity and stability of factor VIII protein.
            Thromb Haemost. 2014;111(1): 58-66

            Pavlova A, Delev D, Pezeshkpoor B, Müller J, Oldenburg J
            Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one- stage and chromogenic factor VIII activity assays.
            Thromb Haemost. 2014;111(5): 851-61

            Brackmann HH
            Twenty years of treatment with Beriate® P.
            Thromb Res. 2014;134 Suppl : S1-3

            Brackmann HH
            Legal requirements for optimal haemophilia treatment in Germany.
            Thromb Res. 2014;134 Suppl : S68-71

            Oldenburg J, Brackmann HH
            Prophylaxis in adult patients with severe haemophilia A.
            Thromb Res. 2014;134 Suppl : S33-7

            Ruehl Heiko, Schroeder Lars, Mueller Jens, Fimmers Rolf, Sukhitashvili Shorena, Welz Julia, Kuhn WaltherC, Oldenburg Johannes, Rudlowski Christian, Poetzsch Bernd
            Tamoxifen induces resistance to activated protein C
            Thromb Res. 2014;133(5): 886-891

            Schindewolf M, Steindl J, Beyer-Westendorf J, Schellong S, Dohmen PM, Brachmann J, Madlener K, Pötzsch B, Klamroth R, Hankowitz J, Banik N, Eberle S, Kropff S, Müller MM, Lindhoff-Last E

            Frequent off-label use of fondaparinux in patients with suspected acute heparin-induced thrombocytopenia (HIT)--findings from the GerHIT multi-centre registry study.
            Thromb Res. 2014;134(1): 29-35

            Watzka M, Geisen C, Scheer M, Wieland R, Wiegering V, Dörner T, Laws HJ, Gümrük F, Hanalioglu S, Unal S, Albayrak D, Oldenburg J
            Bleeding and non-bleeding phenotypes in patients with GGCX gene mutations.
            Thromb Res. 2014;134(4): 856-65

            Veröffentlichungen 2013

            Schindler E, Hertfelder HJ
            [Hemostasis and antifibrinolytic therapy in major pediatric surgery].
            Anasthesiol Intensivmed Notfallmed Schmerzther. 2013;48(7-8): 454-61; quiz 462

            Ivaskevicius V, Biswas A, Thomas A, Lyonga S, Rott H, Halimeh S, Kappert G, Klammroth R, Scholz U, Eberl W, Harbrecht U, Gnida C, Hertfelder HJ, Marquardt N, Oldenburg J
            A common F13A1 intron 1 variant IVS1+12(A) is associated with mild FXIII deficiency in Caucasian population.
            Ann Hematol. 2013;92(7): 975-9

            Lodemann P, Kolbeck H, Held TK, Ivaskevicius V, Oldenburg J, Schweigerer L, Ludwig WD, Peetz D
            Acquired deficiency of coagulation factor XIII--possible evidence for a new link between coagulation and infection from a case.
            Ann Hematol. 2013;92(3): 427-9

            Pollmann H, Klamroth R, Vidovic N, Kriukov AY, Epstein J, Abraham I, Spotts G, Oldenburg J
            Prophylaxis and quality of life in patients with hemophilia A during routine treatment with ADVATE [antihemophilic factor (recombinant), plasma/albumin-free method] in Germany: a subgroup analysis of the ADVATE PASS post-approval, non-interventional study
            Ann Hematol. 2013;92(5): 689-98
              Zeitler H, Goldmann G, Marquardt N, Ulrich-Merzenich G
              Long term outcome of patients with acquired haemophilia--a monocentre interim analysis of 82 patients.
              Atheroscler Suppl. 2013;14(1): 223-8

              Bevans CG, Krettler C, Reinhart C, Tran H, Koßmann K, Watzka M, Oldenburg J
              Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay.
              Biochim Biophys Acta. 2013;1830(8): 4202-10

              Astermark J, Donfield SM, Gomperts ED, Schwarz J, Menius ED, Pavlova A, Oldenburg J, Kessing B, DiMichele DM, Shapiro AD, Winkler CA, Berntorp E, Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort , Liesner R, Windyga J, Klukowska A, Kavakli K, Santagostino E, Mancuso ME, DiMichele D, Giardina P, Rivard G, Oldenburg J, van den Berg M, Schutgens R, Ewing N, Astermark J, Mäkipernaa A, Schwyzer R, Shapiro A, Altisent C, Bianco RP, Ducore J, Leissinger C, Ruiz-Sáez A, Collins P, Monahan P, Peters M, Valentino L, Alvárez M, Jíminez-Yuste V, Chalmers E, Jurgutis R, Kouides P, Pollman H, Thornburg C, Huang J, Male C, Önundarson P, Solano MH, Cnossen MH, Escobar M, Gomperts E, Iyer R, Makris M, Rangarajan S, Warrier I, Chitlur M, de Moerloose P, Evans G, Gruppo R, Janic D, Micic D
              The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.
              Blood. 2013;121(8): 1446-54

              Czogalla KJ, Biswas A, Wendeln AC, Westhofen P, Müller CR, Watzka M, Oldenburg J
              Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces.
              Blood. 2013;122(15): 2743-50
                Eckhardt CL, van Velzen AS, Peters M, Astermark J, Brons PP, Castaman G, Cnossen MH, Dors N, Escuriola-Ettingshausen C, Hamulyak K, Hart DP, Hay CR, Haya S, van Heerde WL, Hermans C, Holmström M, Jimenez-Yuste V, Keenan RD, Klamroth R, Laros-van Gorkom BA, Leebeek FW, Liesner R, Mäkipernaa A, Male C, Mauser-Bunschoten E, Mazzucconi MG, McRae S, Meijer K, Mitchell M, Morfini M, Nijziel M, Oldenburg J, Peerlinck K, Petrini P, Platokouki H, Reitter-Pfoertner SE, Santagostino E, Schinco P, Smiers FJ, Siegmund B, Tagliaferri A, Yee TT, Kamphuisen PW, van der Bom JG, Fijnvandraat K, INSIGHT Study Group
                Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A.
                Blood. 2013;122(11): 1954-62

                Gouw SC, van den Berg HM, Fischer K, Auerswald G, Carcao M, Chalmers E, Chambost H, Kurnik K, Liesner R, Petrini P, Platokouki H, Altisent C, Oldenburg J, Nolan B, Garrido RP, Mancuso ME, Rafowicz A, Williams M, Clausen N, Middelburg RA, Ljung R, van der Bom JG, PedNet and Research of Determinants of INhibitor development (RODIN) Study Group , Altisent C, Auerswald G, Carcao M, Chalmers E, Chambost H, Cid A, Claeyssens S, Clausen N, Fischer K, van Geet Ch, Peerlinck K, Kenet G, Kobelt R, Kreuz W, Escuriola C, Kurnik K, Liesner R, Ljung R, Mäkipernaa A, Molinari A, Muntean W, Nolan B, Oldenburg J, Pérez Garrido R, Petrini P, Platokouki H, Rafowicz A, Rivard G, Santagostino E, Mancuso ME, Thomas A, Williams M, Gouw SC, van der Bom JG, van den Berg HM
                Intensity of factor VIII treatment and inhibitor development in children with severe hemophilia A: the RODIN study.
                Blood. 2013;121(20): 4046-55

                Pavlova A
                F8 gene and phenotype: single player in a team?
                Blood. 2013;121(19): 3784-5
                  Peng WM, Maintz L, Allam JP, Raap U, Gütgemann I, Kirfel J, Wardelmann E, Perner S, Zhao W, Fimmers R, Walgenbach K, Oldenburg J, Schwartz LB, Novak N
                  Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis.
                  Blood. 2013;122(10): 1779-88

                  Whelan SF, Hofbauer CJ, Horling FM, Allacher P, Wolfsegger MJ, Oldenburg J, Male C, Windyga J, Tiede A, Schwarz HP, Scheiflinger F, Reipert BM
                  Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients.
                  Blood. 2013;121(6): 1039-48

                  Marinova M, Lütjohann D, Breuer O, Kölsch H, Westhofen P, Watzka M, Mengel M, Stoffel- Wagner B, Hartmann G, Coch C, Oldenburg J
                  VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation.
                  Eur J Clin Pharmacol. 2013;69(3): 467-75

                  Repessé Y, Peyron I, Dimitrov JD, Dasgupta S, Moshai EF, Costa C, Borel-Derlon A, Guillet B, D'Oiron R, Aouba A, Rothschild C, Oldenburg J, Pavlova A, Kaveri SV, Lacroix-Desmazes S, ABIRISK consortium
                  Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.
                  Haematologica. 2013;98(10): 1650-5

                  Yadegari H, Driesen J, Pavlova A, Biswas A, Ivaskevicius V, Klamroth R, Oldenburg J
                  Insights into pathological mechanisms of missense mutations in C-terminal domains of von Willebrand factor causing qualitative or quantitative von Willebrand disease.
                  Haematologica. 2013;98(8): 1315-23

                  Pahl S, Pavlova A, Driesen J, Müller J, Pötzsch B, Oldenburg J
                  In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile.
                  Haemophilia. 2013;19(3): 392-8
                    Rost S, Aumann V, Nanda I, Oldenburg J, Müller CR
                    Mild haemophilia A in a female patient with a large X-chromosomal deletion and a missense mutation in the F8 gene--a case report.
                    Haemophilia. 2013;19(5): e310-3

                    Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E, Hemophilia Inhibitor Genetics Study Combined Cohort , Liesner R, Windyga J, Klukowska A, Kavakli K, Santagostino E, Mancuso ME, DiMichele D, Giardina P, Rivard G, Oldenburg J, van den Berg M, Schutgens R, Ewing N, Astermark J, Mäkipernaa A, Schwyzer R, Shapiro A, Altisent C, Peréz Bianco R, Ducore J, Leissinger C, Ruiz-Sáez A, Collins P, Monahan P, Peters M, Valentino L, Alvárez M, Jíminez-Yuste V, Chalmers E, Jurgutis R, Kouides P, Pollman H, Thornburg C, Huang J, Male C, Önundarson P, Solano MH, Cnossen MH, Escobar M, Gomperts E, Iyer R, Makris M, Rangarajan S, Warrier I, Chitlur M, de Moerloose P, Evans G, Gruppo R, Janic D, Micic D
                    F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.
                    Haemophilia. 2013;19(1): 113-8

                    Zimmermann MA, Gehrig A, Oldenburg J, Müller CR, Rost S
                    Analysis of F8 mRNA in haemophilia A patients with silent mutations or presumptive splice site mutations.
                    Haemophilia. 2013;19(2): 310-7

                    Oldenburg J, Kurnik K
                    Hamburg Hemophilia Symposium 2012
                    Hamostaseologie. 2013;33 1(4A): S1-S1

                    Zimmermann MA, Hansmann T, Haaf T, Oldenburg J, Muller CR, Rost S
                    Methylation analysis of the promoter region and intron 1 of the factor VIII gene in haemophilia A patients
                    Hamostaseologie. 2013;33 1(4A): S46-S49

                    Lane J, McLaren PJ, Dorrell L, Shianna KV, Stemke A, Pelak K, Moore S, Oldenburg J, Alvarez-Roman MT, Angelillo-Scherrer A, Boehlen F, Bolton-Maggs PH, Brand B, Brown D, Chiang E, Cid-Haro AR, Clotet B, Collins P, Colombo S, Dalmau J, Fogarty P, Giangrande P, Gringeri A, Iyer R, Katsarou O, Kempton C, Kuriakose P, Lin J, Makris M, Manco-Johnson M, Tsakiris DA, Martinez-Picado J, Mauser-Bunschoten E, Neff A, Oka S, Oyesiku L, Parra R, Peter-Salonen K, Powell J, Recht M, Shapiro A, Stine K, Talks K, Telenti A, Wilde J, Yee TT, Wolinsky SM, Martinson J, Hussain SK, Bream JH, Jacobson LP, Carrington M, Goedert JJ, Haynes BF, McMichael AJ, Goldstein DB, Fellay J, NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI)
                    A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.
                    Hum Mol Genet. 2013;22(9): 1903-10

                    Biswas A, Thomas A, Bevans CG, Ivaskevicius V, Oldenburg J
                    In vitro secretion deficits are common among human coagulation factor XIII subunit B missense mutants: correlations with patient phenotypes and molecular models.
                    Hum Mutat. 2013;34(11): 1490-500

                    Fregin A, Czogalla KJ, Gansler J, Rost S, Taverna M, Watzka M, Bevans CG, Müller CR, Oldenburg J
                    A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay.
                    J Thromb Haemost. 2013;11(5): 872-80
                      Pezeshkpoor B, Zimmer N, Marquardt N, Nanda I, Haaf T, Budde U, Oldenburg J, El-Maarri O
                      Deep intronic 'mutations' cause hemophilia A: application of next generation sequencing in patients without detectable mutation in F8 cDNA.
                      J Thromb Haemost. 2013;11(9): 1679-87

                      Pötzsch B
                      Med Klin Intensivmed Notfmed. 2013;108(4): 325-34; quiz 335-6

                      Pavlova A, Oldenburg J
                      Defining severity of hemophilia: more than factor levels.
                      Semin Thromb Hemost. 2013;39(7): 702-10

                      Hammerstingl C, Pötzsch B, Nickenig G
                      Resolution of giant left atrial appendage thrombus with rivaroxaban.
                      Thromb Haemost. 2013;109(4): 583-4

                      Schwaab R, Pavlova A, Albert T, Caspers M, Oldenburg J
                      Significance of F8 missense mutations with respect to inhibitor formation.
                      Thromb Haemost. 2013;109(3): 464-70

                      Rogenhofer S, Hauser S, Breuer A, Fechner G, Mueller SC, Oldenburg J, Goldmann G
                      Urological surgery in patients with hemorrhagic bleeding disorders Hemophilia A, Hemophilia B, von Willebrand disease: a retrospective study with matched pairs analysis.
                      World J Urol. 2013;31(3): 703-7

                      Veröffentlichungen 2012

                      Borck G, Kakar N, Hoch J, Friedrich K, Freudenberg J, Nürnberg G, Yilmaz R, Daud S, Baloch DM, Nürnberg P, Oldenburg J, Ahmad J, Kubisch C.
                      An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group.
                      Hum Genet. 2012; 131:209-216 epub 2011 Jul 15

                      Caspers M, Pavlova A, Driesen J, Harbrecht U, Klamroth R, Kadar J, Fischer R, Kemkes-Matthes B, Oldenburg J.
                      Deficiencies of antithrombin, protein C and protein S - Practical experience in genetic analysis of a large patient cohort.
                      Thromb Haemost. 2012 Jul 25;108(2):247-57. Epub 2012 May 25.

                      Geiser F, Gessler K, Conrad R, Imbierowicz K, Albus C, Harbrecht U.
                      Can activation of coagulation and impairment of fibrinolysis in patients with anxiety and depression be reversed after improvement of psychiatric symptoms?: results of a pilot study.
                      J Nerv Ment Dis. 2012 Aug;200(8):721-3.

                      Gringeri A, Ofosu FA, Grancha S, Oldenburg J, Ewing NP, Federici AB.
                      Understanding FVIII/VWF complex--report from a symposium of XXIX WFH meeting 2010.
                      Haemophilia. 2012 May;18(3):469-75. doi: 10.1111/j.1365-2516.2011.02655.x. Epub 2011 Sep 22.

                      Müller J, Friedrich M, Becher T, Braunstein J, Kupper T, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G, Pötzsch B.
                      Monitoring of plasma levels of activated protein C using a clinically applicable oligonucleotide-based enzyme capture assay.
                      J Thromb Haemost. 2012 Mar;10(3):390-8. doi: 10.1111/j.1538-7836.2012.04623.x.

                      Rohrbach F, Fatthalla MI, Kupper T, Pötzsch B, Müller J, Petersen M, Pedersen EB, Mayer G.
                      Chemical maturation of a bivalent aptamer by single domain variation.
                      Chembiochem. 2012 Mar 19;13(5):631-4. doi: 10.1002/cbic.201200015. Epub 2012 Feb 13. No abstract available.

                      Rühl H, Müller J, Harbrecht U, Fimmers R, Oldenburg J, Mayer G, Pötzsch B.Thrombin inhibition profiles in healthy individuals and thrombophilic patients.
                      Thromb Haemost. 2012 May 2;107(5):848-53. Epub 2012 Jan 25.

                      Singer H, Walier M, Nüsgen N, Meesters C, Schreiner F, Woelfle J, Fimmers R, Wienker T, Kalscheuer VM, Becker T, Schwaab R, Oldenburg J, El-Maarri O.
                      Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci.
                      Hum Mol Genet. 2012 Jan 1;21(1):219-35. Epub 2011 Oct 4.

                      Zimmermann MA, Meier D, Oldenburg J, Müller CR, Rost S.
                      Identification and characterization of mutations in the promoter region of the factor VIII gene.
                      J Thromb Haemost. 2012; 10(2):314-7 Epub 2011 Dec 3.

                      Ehren K, Lamberti C, Poetzsch B, Majores M,Strach K, Sauerbruch T, Wasmuth JC
                      Massive hypercoagulable state despite full-dose anticoagulant treatment in a patient with occult malignancy: considerations concerning chemotherapy without definitive diagnosis.
                      BMJ Case Rep 2010 Jul 7;2010. pii: bcr0120091471. doi: 10.1136/bcr.01.2009.1471

                      Veröffentlichungen 2011

                      Bartsch I, Sandrock K, Lanza F, Nurden P, Hainmann I, Pavlova A, Greinacher A, Tacke U, Barth M, Busse A, Oldenburg J, Bommer M, Strahm B, Superti-Furga A, Zieger B.
                      Deletion of human GP1BB and SEPT5 is associated with Bernard-Soulier syndrome, platelet secretion defect, polymicrogyria, and developmental delay.
                      Thromb Haemost. 2011 Sep;106(3):475-83.

                      Besmens I, Brackmann HH, Oldenburg J.
                      Comprehensive Care Center Bonn from 1980 to 2009. Changes in the epidemiology and regional composition of the haemophilia population.
                      Hamostaseologie. 2011 Nov;31 Suppl 1:S4-S10. German.

                      Biswas A, Ivaskevicius V, Seitz R, Thomas A, Oldenburg J
                      An update of the mutation profile of Factor 13 A and B genes.
                      Blood Rev. 2011 Sep;25(5):193-204.

                      El-Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz-Lacava A, Nüsgen N, Niemann B, Watzka M, Reinsberg J, van der Ven H, Wienker T, Stoffel-Wagner B, Schwaab R, Oldenburg J.
                      Methylation at Global LINE-1 Repeats in Human Blood Are Affected by Gender but Not by Age or Natural Hormone Cycles
                      PLoS One. 2011 Jan 19;6(1):e16252.

                      Frieling T, Meis K, Kolck UW, Homann J, Hülsdonk A, Haars U, Hertfelder HJ, Oldenburg J, Seidel H, Molderings GJ.
                      Evidence for mast cell activation in patients with therapy-resistant irritable bowel syndrome
                      Z Gastroenterol. 2011 Feb;49(2):191-4. Epub 2011 Feb 4.

                      Geisen C, Luxembourg B, Watzka M, Toennes SW, Sittinger K, Marinova M, von Ahsen N, Lindhoff-Last E, Seifried E, Oldenburg J.
                      Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters.
                      Eur J Clin Pharmacol. 2010 Nov 26. [Epub 2010, print 2011]

                      Geiser F, Conrad R, Imbierowicz K, Meier C, Liedtke R, Klingmüller D, Oldenburg J, Harbrecht U.
                      Coagulation activation and fibrinolysis impairment are reduced in patients with anxiety and depression when medicated with serotonergic antidepressants.
                      Psychiatry Clin Neurosci. 2011 Aug;65(5):518-25.

                      Harbrecht U
                      Old and new anticoagulants.
                      Hamostaseologie, 2011 Feb;31(1):21-7.

                      Jahns M, Friess D, Demarmels Biasiutti F, Kremer Hovinga JA, Alberio L, Oldenburg J, Lämmle B, Colucci G.
                      Massive muscle haematoma three months after starting vitamin K antagonist therapy for deep-vein thrombosis in an antithrombin deficient patient: Another case of factor IX propeptide mutation.
                      Thromb Haemost. 2011 Aug 1;106(2):381-2. Epub 2011 Jun 9.

                      Kroll H, Feldmann K, Zwingel C, Hoch J, Bald R, Bein G, Bayat B, Santoso S.
                      A new platelet alloantigen, Swi(a) , located on glycoprotein Ia identified in a family with fetal and neonatal alloimmune thrombocytopenia.
                      Transfusion. 2011 Aug;51(8):1745-54.

                      Langhans B, Kupfer B, Braunschweiger I, Arndt S, Schulte W, Nischalke HD, Nattermann J, Oldenburg J, Sauerbruch T, Spengler U.
                      Interferon-lambda serum levels in hepatitis C.
                      J Hepatol. 2011 May;54(5):859-65. Epub 2010 Oct 23.

                      Ljung R, Oldenburg J, Auerswald G, van den Berg M, Shima M, DiMichele D.
                      Report of the Fifth meeting of the International Network for Pediatric Hemophilia: a focus on prophylaxis and immune tolerance induction.
                      Int J Hematol. 2011 Oct;94(4):415-21. Epub 2011 Sep 28.

                      Lutz P, Wasmuth JC, Nischalke HD, Vidovic N, Grünhage F, Lammert F, Oldenburg J, Rockstroh JK, Sauerbruch T, Spengler U.
                      Progression of Liver Fibrosis in HIV/HCV Genotype 1 Co-infected Patients is Related to the T Allele of the rs12979860 Polymorphism of the IL28B Gene
                      Eur J Med Res. 2011 Aug 8;16(8):335-41.

                      Luxembourg B, Delev D, Geisen C, Spannagl M, Krause M, Miesbach W, Heller C, Bergmann F, Schmeink U, Grossmann R, Lindhoff-Last E, Seifried E, Oldenburg J, Pavlova A.
                      Molecular basis of antithrombin deficiency
                      Thromb Haemost. 2011 Apr 4;105(4):635-46. Epub Jan 25.

                      Luxembourg B, Schneider K, Sittinger K, Toennes SW, Seifried E, Lindhoff-Last E, Oldenburg J, Geisen C.
                      Impact of pharmacokinetic (CYP2C9) and pharmacodynamic (VKORC1, F7, GGCX, CALU, EPHX1) gene variants on the initiation and maintenance phases of phenprocoumon
                      Thromb Haemost. 2011 Jan 3;105(1):169-80. Epub 2010 Nov 5.

                      Marinova W, Lütjohann D, Westhofen P, Watzka M, Breuer O, Oldenburg J,
                      A validated HPCL method for the determination of vitamin K in human serum - First application in a pharmalogical study
                      Open Clinical Chem J, 2011 (4) 17-27.

                      Mayer G, Müller J, Lünse CE.
                      RNA diagnostics: real-time RT-PCR strategies and promising novel target RNAs.
                      Wiley Interdiscip Rev RNA. 2011 Jan-Feb;2(1):32-41.

                      Mayer G, Rohrbach F, Pötzsch B, Müller J.
                      Aptamer-based modulation of blood coagulation.
                      Hamostaseologie. 2011 Nov;31(4):258-63.

                      Miesbach W, Alesci S, Geisen C, Oldenburg J
                      Association between phenotype and genotype in carriers of haemophilia A
                      Haemophilia. 2011 Mar;17(2):246-51 Epub 2010 Dec 1.

                      Modrow S, Wenzel JJ, Schimanski S, Schwarzbeck J, Rothe U, Oldenburg J, Jilg W, Eis-Hübinger AM.
                      Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates.
                      Vox Sang. May; 100(4):351-8 Epub 2010 Dec 7.

                      Müller J, Becher T, Braunstein J, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G, Pötzsch B
                      Profiling of Active Thrombin in Human Blood by Supramolecular Complexes
                      Angew Chem Int Ed Engl. 2011; 50: 6075-8.

                      Nischalke HD, Berger C, Luda C, Berg T, Müller T, Grünhage F, Lammert F, Coenen M, Krämer B, Körner C, Vidovic N, Oldenburg J, Nattermann J, Sauerbruch T, Spengler U
                      The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.
                      PLoS One. 2011;6(11):e27087. Epub 2011 Nov 7.

                      Oldenburg J
                      Prophylaxis in bleeding disorders
                      Thromb Res. 2011 Jan;127 Suppl 1:S14-7. Epub 2010 Nov 26.

                      Pötzsch B, Ivaskevicius V
                      Haemostasis management of massive bleeding.
                      Hamostaseologie, 2011 Feb;31(1):15-20.

                      Roth L, Marschalek R, Oldenburg J, Oyen F, Schneppenheim R.
                      Characterisation of two novel large F8 deletions in patients with severe haemophilia A and factor VIII inhibitors.
                      Thromb Haemost. 2011 Feb 1;105(2):279-84. Epub 2010 Nov 23

                      Schaafhausen A, Rost S, Oldenburg J, Müller CR.
                      Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation.
                      Thromb Haemost. 2011 Feb 1;105(2):285-94. Epub 2010 Nov 23

                      Schreiner F, El-Maarri O, Gohlke B, Stutte S, Nuesgen N, Mattheisen M, Fimmers R, Bartmann P, Oldenburg J, Woelfle J.
                      Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults.
                      BMC Med Genet. 2011 Sep 1;12(1):115. [Epub ahead of print]

                      Seidel H, Molderings GJ, Oldenburg J, Meis K, Kolck UW, Homann J, Hertfelder HJ
                      Bleeding diathesis in patients with mast cell activation disease
                      Thromb Haemost. 2011 Nov 3;106(5):987-9. Epub 2011 Sep 8.

                      Setty P, Gessi M, Waha A, Hammes J, El-Maarri O, Pietsch T, Waha A.
                      Sensitive Determination of BRAF Copy Number in Clinical Samples by Pyrosequencing.
                      Diagn Mol Pathol. 2011 Sep;20(3):148-57.Aug 11. [Epub ahead of print]

                      Singer H, Nüsgen N, El-Maarri O.
                      SIRPH: an HPLC-based SNuPE for quantitative methylation measurement at specific CpG sites.
                      Methods Mol Biol. 2011;791:89-100.

                      Taubner A, Oldenburg J, Gravius S, Wirtz DC, Berdel P.
                      Homo erectus haemophilus - the haemophilic arthropathy of the leg.
                      Hamostaseologie. 2011 Nov;31 Suppl 1:S46-50. German.

                      Vogel M, Friedrich O, Lüchters G, Holleczek B, Wasmuth J C, Anadol E, Schwarze-Zander C, Nattermann J, Oldenburg J, Sauerbruch T, Rockstroh J K, Spengler U
                      Cancer Risk in HIV-infected Individuals on HAART is Largely Attributed to Oncogenic Infections and State of Immunocompetence
                      Eur J Med Res 2011 Mar 28; 16(3):101-7

                      Walther-Wenke G, Wirsing von König CH, Däubener W, Heiden M, Hoch J, Hornei B, Volkers P; Working party on Bacteria Safety in Transfusion Medicine of the Advisory Board of the German Ministry of Health (Arbeitskreis Blut), Berlin, Germany.
                      Monitoring bacterial contamination of blood components in Germany: effect of contamination reduction measures.
                      Vox Sang. May;100(4):359-366. Epub 2010 Oct 28

                      Watzka M, Geisen C, Bevans CG, Sittinger K, Spohn G, Rost S, Seifried E, Müller CR, Oldenburg J.
                      Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.
                      J Thromb Haemost. 2011 Jan;9(1):109-18. Epub 2010

                      Westhofen P, Watzka M, Marinova M, Hass M, Kirfel G, Mueller J, Bevans CG, Mueller CR, Oldenburg J.
                      Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediates vitamin K-dependent intracellular antioxidant function
                      J Biol Chem. 2011 Apr 29;286(17):15085-94. Epub 2011 Mar 2.

                      Yadegari H, Driesen J, Hass M, Budde U, Pavlova A, Oldenburg J.
                      Large deletions identified in patients with von Willebrand disease using multiple ligation-dependent probe amplification.
                      J Thromb Haemost. 2011 May;9(5):1083-6.

                      Veröffentlichungen 2010

                      Berdel P, Pagenstert G, Randau T, Schott D, Taubner A, Oldenburg J, Seuser A, Wirtz DC, Gravius S.
                      Algorithm for the treatment of the haemophilic arthropathia of the upper ankle join
                      Hamostaseologie. 2010 Nov;30 Suppl 1:S93-6

                      Brackmann HH, Gormsen J
                      Massive factor-VIII infusion in Haemophiliac with factor-VIII inhibitor, high responder. 1977.
                      Haemophilia. 2010 Apr;16(102):2-3.

                      Buff MC, Schäfer F, Wulffen B, Müller J, Pötzsch B, Heckel A, Mayer G.
                      Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency
                      Nucleic Acids Res. 2010 Apr;38(6):2111-8. Epub 2009 Dec 8

                      Goldmann G, Holoborodska Y, Oldenburg J, Schaefer N, Hoeller T, Standop J, Kalff JC, Hirner A, Overhaus M.
                      Perioperative management and outcome of general and abdominal surgery in hemophiliacs.
                      Am J Surg. 2010 May;199(5):702-7..

                      Grünhage F, Wasmuth JC, Herkenrath S, Vidovic N, Goldmann G, Rockstroh J, Lammert F, Oldenburg J, Sauerbruch T, Spengler U.
                      Transient elastography discloses identical distribution of liver fibrosis in chronic hepatitis C between HIV-negative and HIV-positive patients on HAART.
                      Eur J Med Res. 2010 Apr 8;15(4):139-44.

                      Hainmann I, Korinthenberg R, Oldenburg J, Pavlova A, Mader I, Zieger B.
                      Compound heterozygosity of the protein S-gene as a cause of severe cerebral sinovenous thrombosis in a 7-year-old child.
                      Klin Padiatr. 2010 May;222(3):194-5. Epub 2010 May 31.]

                      Heinrich N, Born M, Hoebert E, Verrel F, Simon A, Bode U, Fleischhack G.
                      Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma.
                      Vasa. 2010 Aug;39(3):271-3.

                      Holbro A, Marbet GA, Tran TH, Oldenburg J, Friesewinkel O, Tsakiris DA.
                      Prosthetic heart valves and rare hypersensitivity to vitamin K antagonists resulting from factor IX mutation: how to manage anticoagulation?
                      Haemophilia. 2010 Jan;16(1):187-9. Epub 2009 Oct 5.

                      Ivaskevicius V, Biswas A, Bevans C, Schroeder V, Kohler HP, Rott H, Halimeh S, Petrides PE, Lenk H, Krause M, Miterski B, Harbrecht U, Oldenburg J.
                      Identification of eight novel coagulation factor XIII subunit A mutations: implied consequences for structure and function.
                      Haematologica. 2010 Jun;95(6):956-62. Epub 2010 Feb 23.

                      Ivaskevicius V, Biswas A, Loreth R, Schroeder V, Ohlenforst S, Rott H, Krause M, Kohler HP, Scharrer I, Oldenburg J.
                      Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency.
                      Haemophilia. 2010 Jul 1;16(4):675-82. Epub 2010 Mar 10.

                      Langhans B, Braunschweiger I, Arndt S, Schulte W, Satoguina J, Layland LE, Vidovic N, Hoerauf A, Oldenburg J, Sauerbruch T, Spengler U.
                      Core-specific adaptive regulatory T-cells in different outcomes of hepatitis C.
                      Clin Sci (Lond). 2010 Apr 20;119(2):97-109.

                      Mangold E, Ludwig KU, Birnbaum S, Baluardo C, Ferrian M, Herms S, Reutter H, de Assis NA, Chawa TA, Mattheisen M, Steffens M, Barth S, Kluck N, Paul A, Becker J, Lauster C, Schmidt G, Braumann B, Scheer M, Reich RH, Hemprich A, Pötzsch S, Blaumeiser B, Moebus S, Krawczak M, Schreiber S, Meitinger T, Wichmann HE, Steegers-Theunissen RP, Kramer FJ, Cichon S, Propping P, Wienker TF, Knapp M, Rubini M, Mossey PA, Hoffmann P, Nöthen MM.
                      Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate
                      Nat Genet. 2010 Jan;42(1):24-6. Epub 2009 Dec 20.

                      Meier C, Harbrecht U, Liedtke R, Oldenburg J, Conrad R, Imbierowicz K, Klingmüller D, Geiser F.
                      Relative hyperhomocysteinemia in patients with panic disorder: a case-control study.
                      Neuropsychobiology. 2010 Aug;62(3):164-70. Epub 2010 Jul 14.

                      Moskau S, Smolka K, Semmler A, Schweichel D, Harbrecht U, Müller J, Pohl C, Klockgether T, Linnebank M
                      Common genetic coagulation variants are not associated with ischemic stroke in a casecontrol study
                      Neurol Res. 2010 Jun;32(5):519-22. Epub 2009 Aug 5

                      Müller J.
                      Real-time RT-PCR for automated detection of HIV-1 RNA during blood donor screening.
                      Methods Mol Biol. 2010;630:319-35.

                      Oldenburg J, Goudemand J, Valentino L, Richards M, Luu H, Kriukov A, Gajek H, Spotts G, Ewenstein B
                      Postauthorization safety surveillance of ADVATE [antihaemophilic factor (recombinant), plasma/albumin-free method] demonstrates efficacy, safety and low-risk for immunogenicity in routine clinical practice.
                      Haemophilia. 2010 Nov;16(6):866-77.Epub Jun 22.

                      Oldenburg J, Kurnik K, Huth-Kühne A, Zimmermann R, Abraham I, Klamroth R.
                      AHEAD. Advate in HaEmophilia A outcome Database.
                      Hamostaseologie 2010 Nov;30 Suppl 1:S23-5

                      Oldenburg J, Pavlova A.
                      Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype.
                      Hamostaseologie. 2010 Nov;30(4):207-11

                      Oldenburg J, Zeitler H, Pavlova A.
                      Genetic markers in acquired haemophilia.
                      Haemophilia. 2010 May;16 Suppl 3:41-5.

                      Pavlova A, Zeitler H, Scharrer I, Brackmann HH, Oldenburg J
                      HLA genotype in patients with acquired haemophilia A.
                      Haemophilia. 2010 May;16(102):107-12.

                      Pölcher M, Ellinger J, Willems S, El-Maarri O, Höller T, Amann C, Wolfgarten M, Rudlowski C, Kuhn W, Braun M.
                      Impact of the menstrual cycle on circulating cell-free DNA.
                      Anticancer Res. 2010 Jun;30(6):2235-40.

                      Poralla C, Hertfelder HJ, Oldenburg J, Müller A, Bartmann P, Heep A.
                      Treatment of acute pulmonary haemorrhage in extremely preterm infants with recombinant activated factor VII.
                      Acta Paediatr. 2010 Feb;99(2):298-300.

                      Salazar-Sánchez L, Jiménez-Cruz G, Mendez M, Chaverri P, Alvarado P, Schröder W, Wulff K, Sandoval M, Herrmann FH, Pavlova A, Oldenburg J.
                      Hamostaseologie. 2010 Nov;30 Suppl 1:S150-2
                      Molecular analysis of FVIII gene in severe HA patients of Costa Rica.

                      Vidovic N, Lochowsky RS, Goldmann G, Rockstroh J, Wasmuth JC, Spengler U, Sauerbruch T, Lammert F, Oldenburg J, Grünhage F
                      Correlation of transient elastography with APRI and FIB-4 in a cohort of patients with congenital bleeding disorders and HCV or HIV/HCV coinfection.
                      Haemophilia. 2010 Sep 1;16(5):778-85.

                      Vidovic N, Musso R, Klamroth R, Enriquez MM, Achilles K
                      Postmarketing surveillance study of KOGENATE((R)) Bayer with Bio-Set((R)) in patients with haemophilia A: evaluation of patients' satisfaction after switch to the new reconstitution system.
                      Haemophilia. 2010 Jan 16(1):66-71

                      Yu CF, Peng WM, Oldenburg J, Hoch J, Bieber T, Limmer A, Hartmann G, Barchet W, Eis-Hübinger AM, Novak N.
                      Human plasmacytoid dendritic cells support Th17 cell effector function in response to TLR7 ligation.
                      J Immunol. 2010 Feb 1;184(3):1159-67..

                      Zeitler H, Ulrich-Merzenich G; Goldmann G, Vidovic N, Brackmann H H; Oldenburg J
                      The relevance of the bleeding severity in the treatment of acquired haemophilia - an update of a single-centre experience with 67 patients
                      Haemophilia. 2010 Apr;16(102):95-101.

                      Zimmermann MA, Oldenburg J, Müller CR, Rost S.
                      Characterization of duplication breakpoints in the factor VIII gene.
                      J Thromb Haemost. 2010; 8(12): 2696-704

                      Veröffentlichungen 2009

                      Ahlenstiel G, Woitas RP, Iwan A, Nattermann J, Feldmann G, Rockstroh JK, Oldenburg J, Kupfer B, Sauerbruch T, Spengler U.
                      Effects of the CCR5-Delta32 mutation on hepatitis C virus-specific immune responses in patients with haemophilia.
                      Immunol Invest. 2009;38(1):1-13.
                      Auerswald G, Muntean W, Kemkes-Matthes B, Klamroth R, Krause M, Kurnik K, Oldenburg J, Pabinger-Fasching I, Schramm W, Zimmermann R, Zotz RB.
                      [Relevance of a single dose of 270 microg/kg recombinant factor VIIa for the treatment of patients with haemophilia and inhibitors - Recommendations from the GTH experts]
                      Hämostaseologie. 2009 May;29(2):197-203. German.

                      Birnbaum S, Ludwig KU, Reutter H, Herms S, Steffens M, Rubini M, Baluardo C, Ferrian M, Almeida de Assis N, Alblas MA, Barth S, Freudenberg J, Lauster C, Schmidt G, Scheer M, Braumann B, Bergé SJ, Reich RH, Schiefke F, Hemprich A, Pötzsch S, Steegers-Theunissen RP, Pötzsch B, Moebus S, Horsthemke B, Kramer FJ, Wienker TF, Mossey PA, Propping P, Cichon S, Hoffmann P, Knapp M, Nöthen MM, Mangold E.
                      Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.
                      Nat Genet. 2009 Apr;41(4):473-7. Epub 2009 Mar 8.

                      Bernstaedt M, Kunze C, Brandt J, Hasenmueller S, Oldenburg J, Koerholz D, Mauz-Koerholz C.
                      Haemophiliac pseudotumour: two case reports of patients with moderate haemophilia A.
                      Klin Padiatr. 2009 May-Jun;221(3):172-3. Epub 2009 May 12.

                      Brenner B, Kuperman AA, Watzka M, Oldenburg J.
                      Vitamin K-dependent coagulation factors deficiency.
                      Semin Thromb Hemost. 2009 Jun;35(4):439-46. Epub 2009 Jul 13. Review.

                      Delev D, Pavlova A, Heinz S, Seifried E, Oldenburg J.
                      Factor 5 mutation profile in German patients with homozygous and heterozygous factor V deficiency.
                      Haemophilia. 2009 Sep;15(5):1143-53. Epub 2009 May 26.

                      Egler C, Albert T, Brokemper O, Zabe-Kühn M, Mayer G, Oldenburg J, Schwaab R.
                      Kinetic parameters of monoclonal antibodies ESH2, ESH4, ESH5, and ESH8 on coagulation factor VIII and their influence on factor VIII activity.
                      J Mol Recognit. 2009 Jul-Aug;22(4):301-6.

                      El-Maarri O, Kareta MS, Mikeska T, Becker T, Diaz-Lacava A, Junen J, Nüsgen N, Behne F, Wienker T, Waha A, Oldenburg J, Chédin F.
                      A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation.
                      Hum Mol Genet. 2009 May 15;18(10):1755-68. Epub 2009 Feb 26.

                      Erlacher M, Heiss J, Hainmann I, Uhl M, Budde U, Oldenburg J, Ivaskevicius V, Al-Jamali J, Zajonc H, Superti-Furga A, Zieger B.
                      Novel findings in two patients with late-diagnosed afibrinogenaemia: intraosseous haemorrhage and fingertip necrosis.
                      Haemophilia. 2009 Jul;15(4):980-2. Epub 2009 Apr 7. No abstract available.

                      Hainmann I, Oldenburg J, Pavlova A, Superti-Furga A, Zieger B.
                      Identification of a novel factor X deletion in combination with a missense mutation in the F10 gene - Genotype-phenotype correlation in a girl with severe factor X deficiency.
                      Hämostaseologie. 2009 May;29(2):184-6.

                      Hammerstingl C, Omran H, Tripp C, Poetzsch B.
                      How useful is determination of anti-factor Xa activity to guide bridging therapy with enoxaparin? A pilot study.
                      Thromb Haemost. 2009 Feb;101(2):325-32.

                      Herrmann FH, Wulff K, Auerswald G, Schulman S, Astermark J, Batorova A, Kreuz W, Pollmann H, Ruiz-Saez A, De Bosch N, Salazar-Sanchez L; Greifswald Factor FVII Deficiency Study Group.
                      Factor VII deficiency: clinical manifestation of 717 subjects from Europe and Latin America with mutations in the factor 7 gene.
                      Haemophilia. 2009 Jan;15(1):267-80. Epub 2008 Oct 30.

                      Klamroth R, Gottstein S, Essers E, Landgraf H, Wilaschek M, Oldenburg J.
                      Successful angiographic embolization of recurrent elbow and knee joint bleeds in seven patients with severe haemophilia.
                      Haemophilia. 2009 Jan;15(1):247-52. Epub 2008 Aug 7.

                      Körner C, Krämer B, Schulte D, Coenen M, Mauss S, Fätkenheuer G, Oldenburg J, Nattermann J, Rockstroh JK, Spengler U.
                      Effects of HCV co-infection on apoptosis of CD4+ T-cells in HIV-positive patients.
                      Clin Sci (Lond). 2009 May 14;116(12):861-70.

                      Lütjohann D, Marinova M, Schneider B, Oldenburg J, von Bergmann K, Bieber T, Björkhem I, Diczfalusy U
                      4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man
                      Int J Clin Pharmacol Ther. 2009 Dec;47(12):709-15.

                      Mayer G, Müller J, Mack T, Freitag DF, Höver T, Pötzsch B, Heckel A.
                      Differential regulation of protein subdomain activity with caged bivalent ligands.
                      Chembiochem. 2009 Mar 2;10(4):654-7.

                      Müller J, Isermann B, Dücker C, Salehi M, Meyer M, Friedrich M, Madhusudhan T, Oldenburg J, Mayer G, Pötzsch B.
                      An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor.
                      Chem Biol. 2009 Apr 24;16(4):442-51.

                      Oldenburg J, Salek SZ.
                      Haemophilia care: from paediatrics to geriatrics. Introductory note.
                      Haemophilia. 2009 Jan;15 Suppl 1:1. No abstract available.

                      Oldenburg J, Dolan G, Lemm G.
                      Haemophilia care then, now and in the future.
                      Haemophilia. 2009 Jan;15 Suppl 1:2-7. Review.

                      Pavlova A, Brondke H, Müsebeck J, Pollmann H, Srivastava A, Oldenburg J.
                      Molecular mechanisms underlying hemophilia A phenotype in seven females.
                      J Thromb Haemost. 2009 Jun;7(6):976-82. Epub 2009 Mar 19.

                      Pavlova A, Delev D, Lacroix-Desmazes S, Schwaab R, Mende M, Fimmers R, Astermark J, Oldenburg J.
                      Impact of polymorphisms of the MHC class II, IL-10, TNF-a and CTLA-4 genes on inhibitor development in severe hemophilia A.
                      J Thromb Haemost. 2009 Dec;7(12):2006-2015 Epub Oct 8.

                      Rost S, Pelz HJ, Menzel S, MacNicoll AD, León V, Song KJ, Jäkel T, Oldenburg J, Müller CR.
                      Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?
                      BMC Genet. 2009 Feb 6;10:4.

                      Rox JM, Müller J, Pötzsch B.
                      PCR-Based amplification of platelet mRNA sequences obtained from small-scale platelet samples.
                      Methods Mol Biol. 2009;496:285-92.

                      Schneppenheim R, Schröder J, Obser T, Oyen F, Schneppenheim S, Oldenburg J.
                      The problem of novel FVIII missense mutations for haemophilia A genetic counseling.
                      Hämostaseologie. 2009 May;29(2):158-60.

                      Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J.
                      VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.
                      Thromb Haemost. 2009 Jun;101(6):1044-50.

                      Tiede A, Huth-Kühne A, Oldenburg J, Grossmann R, Geisen U, Krause M, Brand B, Alberio L, Klamroth R, Spannagl M, Knöbl P.
                      Immunosuppressive treatment for acquired haemophilia: current practice and future directions in Germany, Austria and Switzerland.
                      Ann Hematol. 2009 Apr;88(4):365-70. Epub 2008 Dec 16.

                      Watzka M, Westhofen P, Hass M, Marinova M, Pötzsch B, Oldenburg J.
                      Polymorphisms in VKORC1 and GGCX are not major genetic determinants of vitamin K-dependent coagulation factor activity in Western Germans.
                      Thromb Haemost. 2009 Aug;102(2):418-20. No abstract available.

                      Zeitler H, Ulrich-Merzenich G, Panek D, Goldmann G, Vidovic N, Brackmann HH, Oldenburg J.
                      Immunoadsorption in the treatment of Acquired Haemophilia.
                      Atheroscler Suppl. 2009 Dec 29;10(5):122-125.

                      Veröffentlichungen 2008

                      Albert T, Egler C, Jakuschev S, Schuldenzucker U, Schmitt A, Brokemper O, Zabe-Kühn M, Hoffmann D, Oldenburg J, Schwaab R.
                      The B-cell epitope of the monoclonal anti-factor VIII antibody ESH8 characterized by peptide array analysis.
                      Thromb Haemost. 2008 Mar;99(3):634-7. No abstract available

                      Barthels M, Oldenburg J
                      Gerinnungsfaktorenkonzentrate [Clotting factor concentrates]
                      Hämostaseologie. 2008;28(5): 387-99

                      Berdel P, Gravius S, Goldmann G, Pennekamp P, Oldenburg J, Seuser A, Wirtz DC.
                      Das muskuläre Kompartmentsyndrom am Unterarm bei Hemmkörperhämophilie
                      [Muscular compartment syndrome of the forearm in a haemophilia inhibitor patient]
                      Hämostaseologie. 2008 Oct;28 Suppl 1:S45-9. German.

                      Bucerius J, Naubereit A, Joe AY, Ezziddin S, Biermann K, Risse J, Palmedo H, Oldenburg J, Biersack HJ.
                      Subclinical hyperthyroidism seems not to have a significant impact on systemic anticoagulation in patients with coumarin therapy.
                      Thromb Haemost. 2008 Nov;100(5):803-9.

                      Castaman G, Giacomelli SH, Ivaskevicius V, Schroeder V, Kohler HP, Dragani A, Biasioli C, Oldenburg J, Madeo D, Rodeghiero F.
                      Molecular characterization of five Italian families with inherited severe factor XIII deficiency.
                      Haemophilia. 2008 Jan;14(1):96-102. Epub 2007 Nov 20.

                      Delev D, Pavlova A, Heinz S, Blaise MC, Chandra T, Poetsch B, Seifried E, Oldenburg J.
                      Modelling and expression studies of two novel mutations causing factor V deficiency.
                      Thromb Haemost. 2008 Nov;100(5):766-72.

                      Frank C, Wenzel E, Brackmann HH, Oldenburg J
                      Influence of treatment with haemostatic agents on ETP in patients with haemophilia and VWD
                      Hämostaseologie. 2008;28 Suppl. : S83-S83

                      Geiser F, Meier C, Wegener I, Imbierowicz K, Conrad R, Liedtke R, Oldenburg J, Harbrecht U.
                      Association between anxiety and factors of coagulation and fibrinolysis.
                      Psychother Psychosom. 2008;77(6):377-83. Epub 2008 Aug 21

                      Gösswein T, Kocot A, Emmert G, Kreuz W, Martinez-Saguer I, Aygören-Pürsün E, Rusicke E, Bork K, Oldenburg J, Müller CR.
                      Mutational spectrum of the C1INH (SERPING1) gene in patients with hereditary angioedema.
                      Cytogenet Genome Res. 2008;121(3-4):181-8. Epub 2008 Aug 28.

                      Helbling C, Goldmann G, Oldenburg J, Heep A, Muller A, Bartmann P, Franz A
                      Postnatal substitution of factor VIII Considering the genetic predisposition for the occurrence of inhibitors
                      Hämostaseologie. 2008;28 Suppl. : S68-S69

                      Herrmann FH, Wulff K, Strey R, Siegemund A, Astermark J, Schulman S; International Greifswald Registry of FVII deficiency.
                      Variability of clinical manifestation of factor VII-deficiency in homozygous and heterozygous subjects of the European F7 gene mutation A294V.
                      Haematologica. 2008 Aug;93(8):1273-5. Epub 2008 Jun 12.

                      Ivaskevicius V
                      Genetics and clinical presentation of the rare autosomally recessive hermorrhagic diatheses
                      Med. Genet.. 2008;20(2): 204-210

                      Ivaskevicius V, Windyga J, Baran B, Bykowska K, Daugela L, Watzka M, Seifried E, Oldenburg J.
                      The first case of combined coagulation factor V and coagulation factor VIII deficiency in Poland due to a novel p.Tyr135Asn missense mutation in the MCFD2 gene.
                      Blood Coagul Fibrinolysis. 2008 Sep;19(6):531-534.

                      Klamroth R, Gottstein S, Essers E, Landgraf H, Wilaschek M, Oldenburg J.
                      Successful angiographic embolization of recurrent elbow and knee joint bleeds in seven patients with severe haemophilia
                      Haemophilia. 2008 Aug 7. [Epub ahead of print]

                      Knör S, Khrenov A, Laufer B, Benhida A, Grailly SC, Schwaab R, Oldenburg J, Beaufort N, Magdolen V, Saint-Remy JM, Saenko EL, Hauser CA, Kessler H.
                      Efficient factor VIII affinity purification using a small synthetic ligand.
                      J Thromb Haemost. 2008 Mar;6(3):470-7. Epub 2008 Jan 9

                      Marinova M, Westhofen P, Watzka M, Hass M, Muller-Reible C, Lütjohann D, Oldenburg J
                      Comparison of vitamin K1 and K2 kinetics of vitamin K epoxide reductase C1
                      Hämostaseologie. 2008;28 Suppl. : S106-S106

                      Mauser-Bunschoten EP, Jansen NW, Doria AS, Oldenburg J.
                      New images in haemophilia.
                      Haemophilia. 2008 Jul;14 Suppl 3:147-52

                      Müller J, El-Maarri O, Oldenburg J, Pötzsch B, Mayer G.
                      Monitoring the progression of the in vitro selection of nucleic acid aptamers by denaturing high-performance liquid chromatography.
                      Anal Bioanal Chem. 2008 Feb;390(4):1033-7. Epub 2007 Nov 10.

                      Müller J, Freitag D, Mayer G, Pötzsch B.
                      Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase.
                      J Thromb Haemost. 2008 Dec;6(12):2105-12. Epub 2008 Sep 27.

                      J. Oldenburg
                      Comprehensive Care Centre and § 116b SGB V Experiences from the point of view of the health insurance company
                      Immune tolerance therapy for inhibitors in haemophilia A
                      Hämostaseologie. 2008 Oct;28 Suppl 1:S23-5. German.

                      Oldenburg J, Barthels M
                      Congenital coagulopathies and coagulation factor inhibitors
                      Hämostaseologie. 2008;28(5): 335-47 Review; English Abstract)

                      Oldenburg J, Kurnik K
                      Hamburg Haemophilia-Symposium 2007
                      Hämostaseologie. 2008;28 Suppl. : S1-S1

                      Oldenburg J, Marinova M, Müller-Reible C, Watzka M.
                      The vitamin K cycle.
                      Vitam Horm. 2008;78:35-62.

                      Oldenburg J, Rost S, Seidel H, Watzka M, Muller-Reible CR
                      Pharmacogenetics of oral anticoagulation therapy with coumarins
                      Med. Genet.. 2008;20(2): 230-235

                      Oldenburg J, Seidel H, Pötzsch B, Watzka M.
                      New insight in therapeutic anticoagulation by coumarin derivatives.
                      Hämostaseologie. 2008;28(1):44-50.

                      Pavlova A, Diaz-Lacava A, Zeitler H, Satoguina J, Niemann B, Krause M, Scharrer I, Hoerauf A, Wienker T, Oldenburg J
                      Increased frequency of the CTLA-4 49 A/G polymorphism in patients with acquired haemophilia A compared to healthy controls.
                      Haemophilia. 2008 Mar;14(2):355-60. Epub 2007 Dec 10.

                      Pavlova A, Förster T, Delev D, Schröder J, El-Maarri O, Müller-Reible C, Oldenburg J.
                      Heterozygous large deletions of Factor 8 gene in females identified by multiplex PCR-LC.
                      Haemophilia. 2008 May;14(3):599-606. Epub 2008 Jan 22.

                      Pavlova A, Hertfelder HJ
                      Monogenetic thrombophilic risk factors
                      Med. Genet.. 2008;20(2): 211-217

                      Pötzsch B
                      Factor V Leiden and prothrombin G20210A mutations. Genetic testing and its effect on treatment
                      Med. Genet.. 2008;20(2): 218-222

                      Rost S, Loeffler S, Pavlova A, Mueller CR, Oldenburg J.
                      Detection of large duplications within the factor VIII gene by MLPA
                      J Thromb Haemost. 2008 Nov;6(11):1996-9. Epub 2008 Aug 22.

                      Satoguina JS, Adjobimey T, Arndts K, Hoch J, Oldenburg J, Layland LE, Hoerauf A.
                      Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta.
                      Eur J Immunol. 2008 Nov;38(11):3101-13.

                      Schneider B, Fryer JF, Oldenburg J, Brackmann HH, Baylis SA, Eis-Hübinger AM.
                      Frequency of contamination of coagulation factor concentrates with novel human parvovirus PARV4.
                      Haemophilia. 2008 Sep;14(5):978-86. Epub 2008 Jun 28.

                      Schwaab R, Rost S, Schroder J, Muller-Reible CR, Oldenburg J
                      Genetics and clinical presentation of haemophilia A and B
                      Med. Genet.. 2008;20(2): 190-196

                      Seuser A, Niemann B, Pennekamp PH, Wirtz DCh, Oldenburg J, Berdel P.
                      Rückenschmerzen und Hämophilie [Backpain and haemophilia]
                      Hämostaseologie. 2008 Oct;28 Suppl 1:S50-1. German.

                      Siegel K, Rost S, Mueller CR, Oldenburg J
                      Recombinant expression of wildtype and mutated gamma-glutamyl carboxylase
                      Hämostaseologie. 2008;28 Suppl. : S104-S105 (Impact(2006)=0, Typ=proceedings paper)

                      Srour MA, Grupp J, Aburubaiha Z, Albert T, Brondke H, Oldenburg J, Schwaab R.
                      Modified expression of coagulation factor VIII by addition of a glycosylation site at the N terminus of the protein.
                      Ann Hematol. 2008 Feb;87(2):107-12. Epub 2007 Sep 26

                      Srour MA, Grupp J, Aburubaiha Z, Albert T, Brondke H, Oldenburg J, Shwaab R
                      Modifizierte Sekretion des Faktors VIII infolge einer zusätzlichen Glykosilierung am N-Terminus
                      Hämostaseologie. 2008;28 Suppl. : S99-S100

                      Tiede A, Huth-Kuhne A, Oldenburg J, Grossmann R, Geisen U, Krause M, Brand B, Alberio L, Klamroth R, Spannagl M, Knobl P
                      Immunosuppression in acquired haemophilia in Germany, Austria and Switzerland
                      Hämostaseologie. 2008;28 Suppl. : S29-S30

                      Ulrich S, Brand B, Speich R, Oldenburg J, Asmis L.
                      Congenital hypersensitivity to vitamin K antagonists due to FIX propeptide mutation at locus -10: a (not so) rare cause of bleeding under oral anticoagulant therapy in Switzerland.
                      Swiss Med Wkly. 2008 Feb 23;138(7-8):100-7.

                      Wenzel F, Baertl A, Zimmermann N, Hohlfeld T, Giers G, Oldenburg J, Assert R.
                      Different behaviour of soluble CD40L concentrations can be reflected by variations of preanalytical conditions.
                      Clin Hemorheol Microcirc. 2008;39(1-4):417-22.

                      Veröffentlichungen 2007

                      Astermark J, Wang X, Oldenburg J, Berntorp E, Lefvert AK; MIBS Study Group.
                      Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia A
                      J Thromb Haemost. 2007 Feb;5(2):263-5.

                      Aygoren-Pursun E, Saguer IM, Rusicke E, Louwen F, Geka F, Ivaskevicius V, Oldenburg J, Klingebiel T, Kreuz W.
                      Retrochorionic hematoma in congenital afibrinogenemia: Resolution with fibrinogen concentrate infusions
                      Am J Hematol. 2007 Apr;82(4):317-20.

                      Bucerius J, Wallny T, Brackmann HH, Joe AY, Roedel R, Biersack HJ, Palmedo H.
                      Rhenium-186 hydroxyethylidenediphosphonate (Re-186 HEDP) for the treatment of hemophilic arthropathy - First results
                      Clin J Pain. 2007 Sep;23(7):612-8.

                      Crew VK, Mallinson G, Green C, Poole J, Uchikawa M, Tani Y, Geisen C, Oldenburg J, Daniels G
                      Different inactivating mutations in the LU genes of three individuals with the Lutheran-null phenotype
                      Transfusion. 2007 Mar;47(3):492-8.

                      El-Maarri O, Becker T, Junen J, Manzoor SS, Diaz-Lacava A, Schwaab R, Wienker T, Oldenburg J
                      Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males
                      Hum Genet. 2007 Dec;122(5):505-14

                      Gorschlüter M, Glasmacher A, Sarazin S, Hackbarth F, Hoebert E, Orlopp K, Schmidt-Wolf IG, Mey U.
                      CD4+ T lymphocyte counts after autologous transplantation in multiple myeloma: a retrospective study.
                      Leuk Lymphoma. 2007 Mar;48(3):506-12

                      Hernando JJ, Park TW, Fischer HP, Zivanovic O, Braun M, Pölcher M, Grünn U, Leutner C, Pötzsch B, Kuhn W.
                      Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer
                      Lancet Oncol. 2007 May;8(5):451-4.

                      Ivaskevicius V, Seitz R, Kohler HR, Schroeder V, Muszbek L, Ariens RA, Seifried E, Oldenburg J; Study Group.
                      International Registry on Factor XIII Deficiency: A basis formed mostly on European data
                      Thromb Haemost. 2007 Jun;97(6):914-21

                      Ivaskevicius V, Windyga J, Baran B, Schroeder V, Junen J, Bykowska K, Seifried E, Kohler HP, Oldenburg J
                      Phenotype-genotype correlation in eight Polish patients with inherited Factor XIII deficiency: identification of three novel mutations
                      Haemophilia. 2007 Sep;13(5):649-57.

                      Kupfer B, Sing T, Schüffler P, Hall R, Kurz R, McKeown A, Schneweis KE, Eberl W, Oldenburg J, Brackmann HH, Rockstroh JK, Spengler U, Däumer MP, Kaiser R, Lengauer T, Matz B
                      Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1
                      J Med Virol. 2007 Nov;79(11):1629-39.

                      Mikeska T, Bock C, El-Maarri O, Hübner A, Ehrentraut D, Schramm J, Felsberg J, Kahl P, Büttner R, Pietsch T, Waha A.
                      Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis
                      J Mol Diagn. 2007 Jul;9(3):368-81.

                      Müller J, Eis-Hübinger AM, Däumer M, Kaiser R, Rox JM, Gürtler L, Hanfland P, Pötzsch B.
                      A novel internally controlled real-time reverse transcription-PCR assay for HIV-1 RNA targeting the pol integrase genomic region
                      J Virol Methods. 2007 Jun;142(1-2):127-35.

                      Müller J, Wulffen B, Pötzsch B, Mayer G.
                      Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer
                      Chembiochem. 2007 Dec 17;8(18):2223-6.

                      Ohlenforst S, Mueller J, Rox JM, Oldenburg J, Pötzsch B.
                      Recurrent intracardiac thrombosis as an unusual manifestation of inherited thrombophilia
                      Int J Cardiol. 2007 Jan 18;114(3):380-1.

                      Oldenburg J, Bevans CG, Fregin A, Geisen C, Müller-Reible C, Watzka M
                      Current pharmacogenetic developments in oral anticoagulation therapy: The influence of variant VKORCI and CYP2C9 alleles
                      Thromb Haemost. 2007 Sep;98(3):570-8

                      Oldenburg J, Watzka M, Rost S, Müller CR
                      VKORC1: molecular target of coumarins
                      J Thromb Haemost. 2007 Jul;5 Suppl 1:1-6.

                      Padosch SA, Schmidt PH, Pedal I, Franchy C, Hoch J, Madea B.
                      Medicolegal assessment of blood transfusion errors - An interdisciplinary challenge
                      Forensic Sci Int. 2007 Oct 2;172(1):40-8.

                      Peng WM, Yu CF, Allam JP, Oldenburg J, Bieber T, Hoch J, Eis-Hübinger AM, Novak N.
                      Inhibitory oligodeoxynucleotides downregulate herpes simplex virus-induced plasmacytoid dendritic cell type I interferon production and modulate cell function
                      Hum Immunol. 2007 Nov;68(11):879-87.

                      Pennekamp PH, Wallny TA, Goldmann G, Kraft CN, Berdel P, Oldenburg J, Wirtz DC
                      Flexion contracture in haemophilic knee arthropathy - 10-year follow-up after hamstring release and dorsal capsulotomy
                      Z Orthop Unfall. 2007 May-Jun;145(3):317-21

                      Pollmann H, Externest D, Ganser A, Eifrig B, Kreuz W, Lenk H, Pabinger I, Schramm W, Schwarz TF, Zimmermann R, Zavazava N, Oldenburg J, Klamroth R.
                      Efficacy, safety and tolerability of recombinant factor VIII (REFACTO (R)) in patients with haemophilia A: interim data from a postmarketing surveillance study in Germany and Austria
                      Haemophilia. 2007 Mar;13(2):131-43.

                      Riess FC, Poetzsch B, Madlener K, Cramer E, Doll KN, Doll S, Lorke DE, Kormann J, Mueller-Berghaus G.
                      Recombinant hirudin for cardiopulmonary bypass anticoagulation: A randomized, prospective, and heparin-controlled pilot study
                      Thorac Cardiovasc Surg. 2007 Jun;55(4):233-8.

                      Seuser A, Berdel P, Oldenburg J
                      Rehabilitation of synovitis in patients with haemophilia
                      Haemophilia. 2007 Nov;13 Suppl 3:26-31.

                      Schneppenheim R, Castaman G, Federici A, Kreuz W, Marschalek R, Oldenburg J, Oyen F, Budde U.
                      A common 253-kb deletion involving VWF and TMEM16B in German and Italian patients with severe von Willebrand disease type 3
                      J Thromb Haemost. 2007 Apr;5(4):722-8.

                      von der Brelie C, Kristof RA, Urbach H, Hartmann A, Hertfelder HJ, Poetzsch B
                      Ischemic brain damage triggers overt disseminated intravascular coagulation in a young woman with cerebral venous sinus thrombosis
                      Thromb Haemost. 2007 Dec;98(6):1371-3.

                      Wallny TA, Scholz DT, Oldenburg J, Nicolay C, Ezziddin S, Pennekamp PH, Stoffel-Wagner B, Kraft CN.
                      Osteoporosis in haemophilia - an underestimated comorbidity?
                      Haemophilia. 2007 Jan;13(1):79-84.

                      Watzka M, Nebel A, El Mokhtari NE, Ivandic B, Müller J, Schreiber S, Oldenburg J..
                      Functional promoter polymorphism in the VKORCI gene is no major genetic determinant for coronary heart disease in Northern Germans
                      Thromb Haemost. 2007 Jun;97(6):998-1002.

                      Wojcik K, Vogel M, Voigt E, Kalff JC, Goldmann G, Oldenburg J, Sauerbruch T, Rockstroh JK, Spengler U
                      Antiviral therapy for hepatitis C virus recurrence after liver transplantation in HIV-infected patients: outcome in the Bonn cohort
                      AIDS. 2007 Jun 19;21(10):1363-5.

                      Zeitler H, Ulrich-Merzenich G, Walger P, Bartels M, Goldmann G, Vetter H, Oldenburg J.
                      Treatment of adults with clinically suspected severe thrombotic thrombocytopenic purpura - Experiences of a single centre
                      Transfus Med Hemother 2007;34:64-72

                      Pfeifer H, Wassmann B, Pavlova A, Wunderle L, Oldenburg J, Binckebanck A, Lange T, Hochhaus A, Wystub S, Brück P, Hoelzer D, Ottmann OG
                      Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL).
                      Blood. 2007 Jul 15;110(2):727-34. Epub 2007 Apr 3.

                      Veröffentlichungen 2006

                      Astermark J, Oldenburg J, Carlson J, Pavlova A, Kavakli K, Berntorp E, Lefvert AK.
                      Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A.
                      Blood. 2006 Dec 1;108(12):3739-45. Epub 2006 Aug 22.

                      Astermark J, Oldenburg J, Pavlova A, Berntorp E, Lefvert AK; MIBS Study Group.
                      Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A.
                      Blood. 2006 Apr 15;107(8):3167-72. Epub 2005 Dec 27.

                      Berber E, Fidanci ID, Un C, El-Maarri O, Aktuglu G, Gurgey A, Celkan T, Meral A, Oldenburg J, Graw J, Akar N, Caglayan H.
                      Sequencing of the factor 8(F8) coding regions in 10 Turkish hemophilia A patients reveals three novel pathological mutations, and one rediagnosis of von Willebrand's disease type 2N.
                      Haemophilia. 2006 Jul;12(4):398-400.

                      Berntorp E, Shapiro A, Astermark J, Blanchette VS, Collins PW, Dimichele D, Escuriola C, Hay CR, Hoots WK, Leissinger CA, Negrier C, Oldenburg J, Peerlinck K, Reding MT, Hart C.
                      Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conference.
                      Haemophilia. 2006 Dec;12 Suppl 6:1-7.

                      Djuric U, El-Maarri O, Lamb B, Kuick R, Seoud M, Coullin P, Oldenburg J, Hanash S, Slim R.
                      Familial molar tissues due to mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation.
                      Hum Genet. 2006 Oct;120(3):390-5. Epub 2006 Jul 28

                      El-Maarri O, Brackmann HH, Hanfland P, Oldenburg J.
                      Hemophilia a patients with undetectable mutations: Current knowledge and future directions
                      Transfus Med Hemother. 2006 Jun; 33(3):156-9

                      El-Maarri O, Singer H, Klein C, Watzka M, Herbiniaux U, Brackmann HH, Schroder J, Graw J, Muller CR, Schramm W, Schwaab R, Haaf T, Hanfland P, Oldenburg J.
                      Lack of F8 mRNA: a novel mechanism leading to hemophilia A.
                      Blood. 2006 Apr 1;107(7):2759-65. Epub 2005 Dec 8.

                      El-Maarri O, Slim R.
                      Familial hydatidiform molar pregnancy: the germline imprinting defect hypothesis?
                      Curr Top Microbiol Immunol. 2006;301:229-41.

                      Greinacher A, Kiefel V, Kluter H, Kroll H, Potzsch B, Riess H; Deutsche Gesellschaft fur Transfusionsmedizin und Immunhämatologie; Deutsche Gesellschaft für Thrombose- und Hämostaseforschung; Deutsche Gesellschaft für Hämatologie und Onkologie.
                      [Recommendations for platelet transfusion by the Joint Thrombocyte Working Party of the German Societies of Transfusion Medicine and Immunohaematology (DGTI), Thrombosis and Haemostasis Research (GTH), and Haematology and Oncology (DGHO)]
                      Dtsch Med Wochenschr. 2006 Nov 24;131(47):2675-9.

                      Hanfland P
                      Transfusionsmedizin - Profil und Perspektiven [Transfusion medicine - Profile and perspectives]
                      Transfus Med Hemother. 2006 Jun; 33(3):279-83

                      Heckel A, Buff MC, Raddatz MS, Muller J, Potzsch B, Mayer G.
                      An anticoagulant with light-triggered antidote activity.
                      Angew Chem Int Ed Engl. 2006 Oct 13;45(40):6748-50.

                      Kiefel V, Bassler D, Kroll H, Paes B, Giers G, Ditomasso J, Alber H, Berns M, Wiebe B, Quenzel EM, Hoch J, Greinacher A.
                      Antigen-positive platelet transfusion in neonatal alloimmune thrombocytopenia (NAIT).
                      Blood. 2006 May 1;107(9):3761-3. Epub 2006 Jan 10.

                      Lee SC, Ng SS, Oldenburg J, Chong PY, Rost S, Guo JY, Yap HL, Rankin SC, Khor HB, Yeo TC, Ng KS, Soong R, Goh BC.
                      Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population.
                      Clin Pharmacol Ther. 2006 Mar;79(3):197-205.

                      Linnebank M, Moskau S, Farmand S, Fliessbach K, Kolsch H, Bos M, Grothe C, Becker D, Harbrecht U, Pohl C, Wullner U, Klockgether T.
                      Homocysteine and Carotid Intima-Media Thickness in a German Population. Lack of Clinical Relevance.
                      Stroke. 2006 Nov;37(11):2840-2.

                      Loreth RM, El-Maarri O, Schroder J, Budde U, Herrmann FH, Oldenburg J.
                      Haemophilia A in a female caused by coincidence of a Swyer syndrome and a missense mutation in factor VIII gene.
                      Thromb Haemost. 2006 Apr;95(4):747-8.

                      Müller J, Rox JM, Pötzsch B
                      Tissue factor gene expression analysis in circulating monocytes
                      Transfus Med Hemother. 2006 33 (2): 183-188

                      Negrier C, Gomperts ED, Oldenburg J.
                      The history of FEIBA: a lifetime of success in the treatment of haemophilia complicated by an inhibitor
                      Haemophilia. 2006 Dec;12 Suppl 5:4-13.

                      Oldenburg J.
                      [Current and future prospects in haemostasis]
                      Hamostaseologie. 2006 Jan;26(1):13-21.

                      Oldenburg J, Bevans CG, Muller CR, Watzka M.
                      Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle.
                      Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):347-53.

                      Oldenburg J, El-Maarri O.
                      New insight into the molecular basis of hemophilia A.
                      Int J Hematol. 2006 Feb;83(2):96-102.

                      Oldenburg J, Hertfelder HJ.
                      [Blood coagulation and hemorrhagic diathesis]
                      Pharm Unserer Zeit. 2006;35(1):20-8.

                      Oldenburg J, Ivaskevicius V, Schroder J, Muller CR, Ganguly A.
                      Genetic background and inhibitors in previously untreated or minimally treated young patients with severe haemophilia A treated with sucrose-formulated recombinant factor VIII.
                      Thromb Haemost. 2006 May;95(5):903-5.

                      Oldenburg J, Pavlova A.
                      Genetic risk factors for inhibitors to factors VIII and IX.
                      Haemophilia. 2006 Dec;12 Suppl 6:15-22.

                      Pavlova A, El-Maarri O, Luxembourg B, Lindhoff-Last E, Kochhan L, Bruhn HD, Delev D, Watzka M, Seifried E, Oldenburg J.
                      Detection of heterozygous large deletions in the antithrombin gene using multiplex polymerase chain reaction and denatured high performance liquid chromatography.
                      Haematologica. 2006 Sep;91(9):1264-1267.

                      Pötzsch B, Müller J, Rox JM.
                      Developmental strategies of novel anticoagulants
                      Transfus Med Hemother. 2006 33 (2):200-204

                      Ramos-Lopez E, Jansen T, Ivaskevicius V, Kahles H, Klepzig C, Oldenburg J, Badenhoop K.
                      Protection from type 1 diabetes by vitamin D receptor haplotypes.
                      Ann N Y Acad Sci. 2006 Oct;1079:327-34.

                      Rost S, Geisen C, Fregin A, Seifried E, Muller CR, Oldenburg J.
                      Founder mutation Arg485Pro led to recurrent compound heterozygous GGCX genotypes in two German patients with VKCFD type 1.
                      Blood Coagul Fibrinolysis. 2006 Sep;17(6):503-507.

                      Rox JM, Müller J, Pötzsch B.
                      Platelet transcriptome analysis
                      Transfus Med Hemother. 2006 33 (2):177-182

                      Schroder J, El-Maarri O, Schwaab R, Muller CR, Oldenburg J.
                      Factor VIII intron-1 inversion: frequency and inhibitor prevalence.
                      J Thromb Haemost. 2006 May;4(5):1141-3.

                      Simon M, Franke D, Ludwig M, Aliashkevich AF, Koster G, Oldenburg J, Bostrom A, Ziegler A, Schramm J.
                      Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system.
                      J Neurosurg. 2006 Jun;104(6):945-9.

                      Srour MA, Albert T, Aburubaiha Z, Grupp J, Schmitt A, Schwaab R
                      Gene therapy for hemophilia
                      Transfus Med Hemother. 2006; 33(2):165-168

                      Wallny TA, Brackmann HH, Gunia G, Wilbertz P, Oldenburg J, Kraft CN.
                      Successful pain treatment in arthropathic lower extremities by acupuncture in haemophilia patients.
                      Haemophilia. 2006 Sep;12(5):500-2.

                      Wallny T, Brackmann H, Kraft C, Nicolay C, Pennekamp P
                      Achilles tendon lengthening for ankle equinus deformity in hemophiliacs - 23 patients followed for 1-24 years
                      Acta Orthop. 2006 Feb; 77 (1): 164-168

                      Zeitler H, Ulrich-Merzenich G, Walger P, Dusing R, Vetter H, Brackmann HH.
                      [The modified Bonn Malmo protocol (MBMP) in the treatment of acquired haemophilia A]
                      Dtsch Med Wochenschr. 2006 Jan 27;131(4):141-7. German.

                      Zeitler H, Ulrich-Merzenich G, Walger P, Vetter H, Oldenburg J, Goldmann G, Brackmann HH. Treatment of factor VIII inhibitors with selective IgG immunoadsorption - a single center experience in 50 patients with acquired hemophilia.
                      Transfus Med Hemother. 2006; 33(2):160-4